Structure of PDB 7t7j Chain B Binding Site BS01

Receptor Information
>7t7j Chain B (length=360) Species: 1125630 (Klebsiella pneumoniae subsp. pneumoniae HS11286) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEE
AEQDFRALLNIPSNYKVLFCHGGGRGQFAGIPLNILGDKKVADYVDAGYW
AASAVKEAKKYCTPNVIDAKITVDGKRAVKPMSEWQLTPGAAYLHYCPNE
TIDGIAIDETPNFGDDVIVTADFSSTILSREIDVNRFGVIYAGAQKNIGP
AGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNTPPTFAWYLAGLV
FKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNVPF
QLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLDGVKTLTD
FMLDFERRHG
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain7t7j Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7t7j Crystal Structure of Phosphoserine aminotransferase from Klebsiella pneumoniae subsp. pneumoniae in complex with Pyridoxal phosphate
Resolution1.5 Å
Binding residue
(original residue number in PDB)		N239 T240
Binding residue
(residue number reindexed from 1)		N237 T238
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0008615 pyridoxine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t7j, PDBe:7t7j, PDBj:7t7j
PDBsum7t7j
PubMed
UniProtA6T700|SERC_KLEP7 Phosphoserine aminotransferase (Gene Name=serC)

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