Structure of PDB 7t1u Chain B Binding Site BS01
Receptor Information
>7t1u Chain B (length=107) Species:
9606
(Homo sapiens) [
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GGAPWQAEEWYFGKITRRESERLLLNAENPRGTFLVREGQSQPDYVLSVS
DFDNAKGLNVKHYIIRKLDSGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCPT
Ligand information
>7t1u Chain E (length=7) Species:
32630
(synthetic construct) [
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EPQYEEI
Receptor-Ligand Complex Structure
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PDB
7t1u
Engineered SH2 Domains for Targeted Phosphoproteomics.
Resolution
2.65 Å
Binding residue
(original residue number in PDB)
R158 R178 G180 S182 Q183 K202 H203 Y204 I205 I216 G238
Binding residue
(residue number reindexed from 1)
R17 R37 G39 S41 Q42 K61 H62 Y63 I64 I74 G96
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:7t1u
,
PDBe:7t1u
,
PDBj:7t1u
PDBsum
7t1u
PubMed
35613471
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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