Structure of PDB 7suo Chain B Binding Site BS01

Receptor Information
>7suo Chain B (length=137) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKP
ADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNN
NQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
Ligand information
>7suo Chain D (length=11) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
APRITFGGPSD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7suo SARS-CoV-2 Nucleocapsid Protein Targets a Conserved Surface Groove of the NTF2-like Domain of G3BP1.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		L10 F15 Q18 R32 F33 E117 N122 K123 F124 Y125
Binding residue
(residue number reindexed from 1)		L9 F14 Q17 R31 F32 E116 N121 K122 F123 Y124
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
External links
PDB RCSB:7suo, PDBe:7suo, PDBj:7suo
PDBsum7suo
PubMed35240128
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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