Structure of PDB 7s7c Chain B Binding Site BS01

Receptor Information
>7s7c Chain B (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENQELKRKLNILTRPSGILVNDTKLDGPILQILFMNNAISKQYHQEIEEF
VSNLVKRFEEQQKNDVEKTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEA
FSVVGSVLYFTNFCLDKLGQPLLNENPQLSEGWEIPKYHQVFSHIVSLEG
QHCFNCGSEEHQMKDCPMPQQRYHAEEVEERFGRFKPGVISEELQDALGV
TDKSLPPFIYRMRQLGYPPGWLKEAELENSGLALYDGKSVTYDLSKLVNY
PGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLPIPDMSKFATGITP
FEFENMAESTGMYLRIRSLLKNSPRNQQKN
Ligand information
>7s7c Chain D (length=27) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcgcgcgccaaaaauuuuaaaaaaaa
...........................
Receptor-Ligand Complex Structure
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PDB7s7c Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Resolution3.62 Å
Binding residue
(original residue number in PDB)		F230 C232 G233
Binding residue
(residue number reindexed from 1)		F154 C156 G157
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7s7c, PDBe:7s7c, PDBj:7s7c
PDBsum7s7c
PubMed35688134
UniProtQ6NZY4|ZCHC8_HUMAN Zinc finger CCHC domain-containing protein 8 (Gene Name=ZCCHC8)

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