Structure of PDB 7rwc Chain B Binding Site BS01

Receptor Information
>7rwc Chain B (length=557) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMN
YAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEP
LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM
VVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDC
LSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSD
YYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFF
VKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVR
AIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKY
ESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHD
ESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYI
YWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYH
KPPNAFV
Ligand information
Receptor-Ligand Complex Structure
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PDB7rwc Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		C433 R458
Binding residue
(residue number reindexed from 1)		C408 R433
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030276 clathrin binding
Biological Process
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rwc, PDBe:7rwc, PDBj:7rwc
PDBsum7rwc
PubMed35347313
UniProtQ9DBG3|AP2B1_MOUSE AP-2 complex subunit beta (Gene Name=Ap2b1)

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