Structure of PDB 7r51 Chain B Binding Site BS01

Receptor Information
>7r51 Chain B (length=698) Species: 837 (Porphyromonas gingivalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDEGMWLMQQLGRKYAQMKERGLKMKEYDLYNPNGTSLKDAVVLFDGGCT
GEVVSDRGLVLTNHHCGYDMIQAHSTLEHNYLENGFWAMREADELPNKDI
SVVFIDKIEDVTDYVKKELKAIKDPNSMDYLSPKYLQKLADKKAGKNFSA
KNPGLSVEIKAFYGGNLYLMFTKKTYTDVRLVGAPPSSIGKFGADTDNWI
WPRHTGDFSIFRIYADKNGNPAPYSEDNVPLKPKRFFNISLGGVQENDYA
MIMGFPGTTHRYFTASEVDEWKSIDNDIRIRMRDIRQGVMLREMLADPQI
KIMYSAKYAASQNAYKRAIGANWAIKTRGLRQNKQAMQDRLIAWGAKQGT
PRYEEAVHEIDATVAKRADLRRRYWMIEEGIIRGIEFARSPIPTEDETKA
LQGASARKEAIDKIRTRYSKFANKDYSAEVDKKVAVAMLTEYLKEIPYEN
LPLHLRLVKDRFAGDVQAYVDDIFARSVFGSEAQFDAFAAVPSVEKLAED
PMVLFASSVFDEYRKLYNELRPYDDPILRAQRTYIAGLLEMDGDQDQFPD
ANLTLRFTYGQVKGYSPRDNVYYGHQTTLDGVMEKEDPDNWEFVVDPKLK
AVYERKDFGRYADRSGRMPVAFCATTHTTGGNSGSPVMNANGELIGLNFD
RNWEGVGGDIQYLADYQRSIIVDIRYVLLVIDKVGGCQRLLDEMNIVP
Ligand information
Receptor-Ligand Complex Structure
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PDB7r51 Structure of P. gingivalis DPP11 in complex with the dipeptide Arg-Asp
Resolution1.808 Å
Binding residue
(original residue number in PDB)
H85 K211 N218 W219 N333 T651 G652 G653 S655 F671 D672 R673
Binding residue
(residue number reindexed from 1)
H65 K191 N198 W199 N313 T629 G630 G631 S633 F649 D650 R651
Enzymatic activity
Enzyme Commision number 3.4.14.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0042277 peptide binding
GO:0070009 serine-type aminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0043171 peptide catabolic process
GO:0048588 developmental cell growth
Cellular Component
GO:0009986 cell surface

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Molecular Function

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Cellular Component
External links
PDB RCSB:7r51, PDBe:7r51, PDBj:7r51
PDBsum7r51
PubMed
UniProtB2RID1|DPP11_PORG3 Asp/Glu-specific dipeptidyl-peptidase (Gene Name=dpp11)

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