Structure of PDB 7qzj Chain B Binding Site BS01

Receptor Information
>7qzj Chain B (length=422) Species: 1203592 (Streptomyces sp. HPH0547) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDTDRARERDRRHLWHPWSSVRDRPILVAGEGCRVRDVTGAGYLDAMASA
MNSSCGYAHPALLEAARRQLELLPHFDLSAASHLPAGLAAERIAGLLPAG
LERTFFVNSGSEATEAAVRIAHDHWTNRGEPRDRLVTFAAGYHGTTLVAQ
HLSGLPTNAIHGTAPFPVTRVELPLEPAALRTPEALTLLADAFERAVLDG
PPPAAVMVEPLLNVGGGVVLPDGFLRALRALCDRTGALLIVDEVFCGFGR
TGRMFGFQHDGVTPDLVTMSKGISGGYVPFAALTTTDEVYRSFAADPLLG
GLRYGHTTGGHAVACAVALAVLDVIEERGLVGSAARLGAELLAGLAPLAE
HPEVTDVRGLGLVATVECRQPESAAALVAEAKRQGVLLRQQGRAVMAIPP
LVIDAAEVAELVRAVEQAVARL
Ligand information
Ligand IDPMP
InChIInChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKeyZMJGSOSNSPKHNH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1CN)C
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
FormulaC8 H13 N2 O5 P
Name4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE;
PYRIDOXAMINE-5'-PHOSPHATE
ChEMBLCHEMBL1235353
DrugBankDB02142
ZINCZINC000001532708
PDB chain7qzj Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qzj Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		H324 T325
Binding residue
(residue number reindexed from 1)		H306 T307
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7qzj, PDBe:7qzj, PDBj:7qzj
PDBsum7qzj
PubMed37005433
UniProtS3AT34

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