Structure of PDB 7quv Chain B Binding Site BS01
Receptor Information
>7quv Chain B (length=107) Species:
9606
(Homo sapiens) [
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MSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENK
NEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHH
HKPGLGE
Ligand information
>7quv Chain C (length=18) Species:
32630
(synthetic construct) [
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RSPESVAFPMFQSHWYSG
Receptor-Ligand Complex Structure
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PDB
7quv
High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays.
Resolution
1.85 Å
Binding residue
(original residue number in PDB)
E15 H22 V26 P31 D32 T33 N71 S77 E79
Binding residue
(residue number reindexed from 1)
E9 H16 V20 P25 D26 T27 N65 S71 E73
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005509
calcium ion binding
GO:0005515
protein binding
GO:0008017
microtubule binding
GO:0008270
zinc ion binding
GO:0016209
antioxidant activity
GO:0035662
Toll-like receptor 4 binding
GO:0046872
metal ion binding
GO:0048306
calcium-dependent protein binding
GO:0050544
arachidonate binding
GO:0050786
RAGE receptor binding
Biological Process
GO:0002523
leukocyte migration involved in inflammatory response
GO:0002544
chronic inflammatory response
GO:0006914
autophagy
GO:0006915
apoptotic process
GO:0006919
activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006935
chemotaxis
GO:0006954
inflammatory response
GO:0007267
cell-cell signaling
GO:0010976
positive regulation of neuron projection development
GO:0014002
astrocyte development
GO:0030307
positive regulation of cell growth
GO:0030593
neutrophil chemotaxis
GO:0032119
sequestering of zinc ion
GO:0032496
response to lipopolysaccharide
GO:0034121
regulation of toll-like receptor signaling pathway
GO:0035425
autocrine signaling
GO:0035606
peptidyl-cysteine S-trans-nitrosylation
GO:0035821
modulation of process of another organism
GO:0042742
defense response to bacterium
GO:0043542
endothelial cell migration
GO:0045087
innate immune response
GO:0045113
regulation of integrin biosynthetic process
GO:0050729
positive regulation of inflammatory response
GO:0050832
defense response to fungus
GO:0051092
positive regulation of NF-kappaB transcription factor activity
GO:0051493
regulation of cytoskeleton organization
GO:0060264
regulation of respiratory burst involved in inflammatory response
GO:0061844
antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070488
neutrophil aggregation
GO:0098869
cellular oxidant detoxification
GO:2001244
positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0005886
plasma membrane
GO:0034774
secretory granule lumen
GO:0062023
collagen-containing extracellular matrix
GO:0070062
extracellular exosome
GO:1990660
calprotectin complex
GO:1990662
S100A9 complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7quv
,
PDBe:7quv
,
PDBj:7quv
PDBsum
7quv
PubMed
37198182
UniProt
P06702
|S10A9_HUMAN Protein S100-A9 (Gene Name=S100A9)
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