Structure of PDB 7qpc Chain B Binding Site BS01

Receptor Information
>7qpc Chain B (length=327) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGISWLDIYHVVSATVPLYVSMTLGFLSARHLKLFSPEQCAGINKFVAKF
SIPLLSFQIISENNPFKMSPKLILSDILQKFLVVVVLAMVLRFWHPTGGR
GGKLGWVITGLSISVLPNTLILGMPILSAIYGDEAASILEQIVVLQSLIW
YTILLFLFELNAARAGTMKILLKAWRKLIINPNTYATLIGIIWATLHFRL
GWNLPEMIDKSIHLLSDGGLGMAMFSLGLFMASQSSIIACGTKMAIITML
LKFVLGPALMIASAYCIRLKSTLFKVAILQAALPQGVVPFVFAKEYNLHP
EIISTGVIFGMLIALPTTLAYYFLLDL
Ligand information
Ligand IDE7O
InChIInChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)
InChIKeyJXTHEWSKYLZVJC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385OC(=O)c1ccccc1C(=O)Nc2cccc3ccccc23
OpenEye OEToolkits 2.0.7c1ccc2c(c1)cccc2NC(=O)c3ccccc3C(=O)O
FormulaC18 H13 N O3
Name2-(naphthalen-1-ylcarbamoyl)benzoic acid
ChEMBLCHEMBL2447888
DrugBank
ZINCZINC000000028113
PDB chain7qpc Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qpc Structures and mechanism of the plant PIN-FORMED auxin transporter.
Resolution3.44 Å
Binding residue
(original residue number in PDB)		A47 N117 L119 I120 Q145 Y150 G326 V327 V328
Binding residue
(residue number reindexed from 1)		A48 N118 L120 I121 Q146 Y151 G286 V287 V288
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0010329 auxin efflux transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0009555 pollen development
GO:0009734 auxin-activated signaling pathway
GO:0010315 auxin export across the plasma membrane
GO:0055085 transmembrane transport
GO:0060918 auxin transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qpc, PDBe:7qpc, PDBj:7qpc
PDBsum7qpc
PubMed35768502
UniProtQ9LFP6|PIN8_ARATH Auxin efflux carrier component 8 (Gene Name=PIN8)

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