Structure of PDB 7pmq Chain B Binding Site BS01

Receptor Information
>7pmq Chain B (length=457) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTG
SGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPN
TKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTL
VMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQR
DPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNT
KKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDV
AARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEA
QRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGDV
LGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
CRVRLLK
Ligand information
>7pmq Chain F (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaaggguuucgacccuucccaauauggcuguucgccauuu
<<<<<<<<......>>>>>>>><<.<<<<<.....>>>>>>>
Receptor-Ligand Complex Structure
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PDB7pmq Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution3.22 Å
Binding residue
(original residue number in PDB)		P79 R81 G108 P111 G113 M114 T129 G131 R132 G162 F163 N249 T250 K251 H272 G273 R278 R280 T298 D299 W320
Binding residue
(residue number reindexed from 1)		P79 R81 G108 P111 G113 M114 T129 G131 R132 G162 F163 N249 T250 K251 H272 G273 R278 R280 T298 D299 W320
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmq, PDBe:7pmq, PDBj:7pmq
PDBsum7pmq
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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