Structure of PDB 7pmm Chain B Binding Site BS01

Receptor Information
>7pmm Chain B (length=439) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKT
GSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLP
NTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNT
LVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQ
RDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCN
TKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATD
VAARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEE
AQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGD
VLGADIGKIAVHPAHVYVAVRQAWKQLQIKGKTCRVRLL
Ligand information
>7pmm Chain C (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaacccuucccaaauggcuguucgccauuugggaaggguu
...<<<<<<<<<<<<<<<<<.....>>>>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB7pmm Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		N100 T101 K102 S118 H121 K391 K394 R396 P397 G398 D399 L401 I415 G416 K417 I418 K447
Binding residue
(residue number reindexed from 1)		N101 T102 K103 S119 H122 K392 K395 R397 P398 G399 D400 L402 I406 G407 K408 I409 K430
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmm, PDBe:7pmm, PDBj:7pmm
PDBsum7pmm
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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