Structure of PDB 7pge Chain B Binding Site BS01

Receptor Information
>7pge Chain B (length=198) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INYLVLLDQLEWQRSDNTNNFSWSVNSWIGGDTDRIWLKSEGERSNGETE
AAEAQLLWGHAVGPWWDLVAGVRQDFRPASARTWAAVGFQGLALYNFESE
ITGFVSNGGKAALRLGGEYDVLLTNRLILQPSYEVNFYSQGLTDTELGLR
LRYEIRREFAPYIGVSWNQLYGKTSDMAKREGEKDHQVVFLAGARIWF
Ligand information
Ligand IDC8E
InChIInChI=1S/C16H34O5/c1-2-3-4-5-6-7-9-18-11-13-20-15-16-21-14-12-19-10-8-17/h17H,2-16H2,1H3
InChIKeyFEOZZFHAVXYAMB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O(CCCCCCCC)CCOCCOCCOCCO
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCCCCCCOCCOCCOCCOCCO
FormulaC16 H34 O5
Name(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
ChEMBL
DrugBankDB04233
ZINCZINC000014881140
PDB chain7pge Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7pge PcoB is a defense outer membrane protein that facilitates cellular uptake of copper.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		W101 Q102 R103 N108 F288 A290
Binding residue
(residue number reindexed from 1)		W12 Q13 R14 N19 F190 A192
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
Biological Process
GO:0006878 intracellular copper ion homeostasis
Cellular Component
GO:0009279 cell outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pge, PDBe:7pge, PDBj:7pge
PDBsum7pge
PubMed35762724
UniProtQ47453|PCOB_ECOLX Copper resistance protein B (Gene Name=pcoB)

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