Structure of PDB 7pcv Chain B Binding Site BS01

Receptor Information
>7pcv Chain B (length=116) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RESKTIMLRGLPTTITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAF
VEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNN
FRKRLKCFRCGADKFD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7pcv Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pcv Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Resolution2.42 Å
Binding residue
(original residue number in PDB)
C96 C99 C110
Binding residue
(residue number reindexed from 1)
C93 C96 C107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7pcv, PDBe:7pcv, PDBj:7pcv
PDBsum7pcv
PubMed37454201
UniProtP52756|RBM5_HUMAN RNA-binding protein 5 (Gene Name=RBM5)

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