Structure of PDB 7p6u Chain B Binding Site BS01

Receptor Information
>7p6u Chain B (length=772) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLELPVLPLRNTVVLPHTTTGVDVGRLKSKRAVEEALSADRLLFLVTQKD
PEVDDPAPEDLYAVGTLAVVKQAMRLPDGTLQVMVEARSRARLLSYVAAP
YLRAVGEAIPEPPLKDPELARVLVNEVQEAFERYLQNHKTLRLDRYQQEA
VKSTRDPAILADLVAHHATWTLEEKQTILETPEVEERLKRVLALLLRDLE
RFELDKKIAARVKEQMDQNQREYYLREQMKAIQKELGGGEDFLTEIEELR
ERIEKKGMPEPVKEKALKELKRLERMQPGSPEATVSRTYLDWLLEVPWTE
ADPEVLDISVTKRVLDEDHYGLKEVKERILEYLAVRQLTQGKEVKGHAPI
LCFVGPPGVGKTSLGKSIARSMNRRFHRISLGGVRDEAEIRGHRRTYIGA
LPGKIIQGMKQVGVVNPVFLLDEIDKLSSDWRGDPAAALLEVLDPEQNHT
FTDHYLDVPYDLSKVFFITTANTLSTIPRPLLDRMEVIEIPGYTLHEKRA
IARYFRWPFQVKEAGLEGRLEITDRAIERIVQEYTREAGVRNLDRELSKV
ARKAAKDYLEKPWEGVRVVDAEDLEAYLGVPKYRPDRAEKEPQVGAAQGL
AWTPYGGTLLTIEAVAVPGTGKVNLTGNLGEVMKESAHAALTYLRAHREE
WGLPEGFHKDYDLHIHVPEGATPKDGPSAGITIATALASALTGRPVRMDI
AMTGEITLRGRVLPIGGVKEKLLAAHQAGIHRVILPKENAAELKEVPEEI
LKDLEIHFVEEVGEVLKLLLLP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p6u Cryo-EM structure of the full-length Lon protease from Thermus thermophilus.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		Y402 I403
Binding residue
(residue number reindexed from 1)		Y397 I398
Enzymatic activity
Enzyme Commision number 3.4.21.53: endopeptidase La.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0008236 serine-type peptidase activity
GO:0016887 ATP hydrolysis activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0030163 protein catabolic process
GO:0034605 cellular response to heat
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7p6u, PDBe:7p6u, PDBj:7p6u
PDBsum7p6u
PubMed34591981
UniProtQ72KS4|LON1_THET2 Lon protease 1 (Gene Name=lon1)

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