Structure of PDB 7osk Chain B Binding Site BS01

Receptor Information
>7osk Chain B (length=360) Species: 583356 (Ignisphaera aggregans DSM 17230) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVIINPVPGLPVDFIRGVDASEAPWIIELGGKYYDENGVERDLLDILKEN
GVNWIRLRVWNDPYDEQGRPYGGGNCDLPRMTDFAAKAKAKGFGVLIDFH
YSDWWADPSKQSKPKAWANLSYPELVEAVYNWTYNALKYMAEHNALPDMV
QIGNEINNGFLWPDGSAANWTQFVGLLKAAISAVKDVNPNIKIVIHLAGV
KADFYINFIDRLINSGVSFDVIAISFYPYWHGTMDDFRNLVRTLVQRYDK
KILVAETAYAWTLDDSDGHPNIFGSRDLEVKGGYKASIQGQASFIRDLIA
ALYEEGKDKALGIFYWGATWIPYPGAGWKTGEGNPWENQALFDFNGRALP
SLKVFRLVYE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7osk Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7osk Engineering the substrate binding site of the hyperthermostable archaeal endo-beta-1,4-galactanase from Ignisphaera aggregans.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		D301 D303 H305 N307 N370 E373
Binding residue
(residue number reindexed from 1)		D265 D267 H269 N271 N334 E337
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.89: arabinogalactan endo-beta-1,4-galactanase.
Gene Ontology
Molecular Function
GO:0015926 glucosidase activity

View graph for
Molecular Function
External links
PDB RCSB:7osk, PDBe:7osk, PDBj:7osk
PDBsum7osk
PubMed34530892
UniProtE0SSW8

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