Structure of PDB 7oem Chain B Binding Site BS01

Receptor Information
>7oem Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYCQHFVDTGHRPQNFIRDVRELIRLKDELIAKSNTPPMYLQADIEAFDI
RELTPKFDVILLEPPLEEYYRKCWTWDDIMKLEIDEIAAPRSFIFLWCGS
GEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPLDPKAVFQRTKEHCLMGI
KGTDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGR
DSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7oem Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oem Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D157 H332 H336
Binding residue
(residue number reindexed from 1)		D28 H183 H187
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7oem, PDBe:7oem, PDBj:7oem
PDBsum7oem
PubMed
UniProtQ9HCE5|MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Gene Name=METTL14)

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