Structure of PDB 7o0h Chain B Binding Site BS01

Receptor Information
>7o0h Chain B (length=523) Species: 2170205 (White-tufted-ear marmoset simian foamy virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPPLLQLPVEVKKTELNGFWDTGAQITCIPEAFLKLKFKVLGRKVEEVTT
SPFDYVIISPSDIPWYKPQPLELTVKLPVQDFKKELINKANINNEEKKQL
AKLLDKYDVLWQQWENQVGHRKIPPHNIATGTVAPRPQRQYHINTKAKPS
IQQVIDDLLKQGVLIKQTSVMNTPIYPVPKPDGKWRMVLDYRAVNKTVPL
IRQKYKSTIDLSNGFWAHPITKDSQWITAFTWEGKQHVWTRLPQGFLNSP
ALFTADVVDLLKNIPGISVYVDDIYFSTETVSEHLKILEKVFKILLEAGY
IVSLKKSALLRYEVTFLGFSITQTQNITSPRTLKELQSILGLFNFARNFV
PNFSEIIKPLYSLISTAEGNNIKWTSEHTRYLEEIVSALNHAGNLEQRDN
ESPLVVKLNASPKTGYIRYYNKQKPIAYASHVFTNTELKFTPLEKLLVTM
HKALIKAIDLALGQPIEVYSPIISMQKLQKTPLPERKALSTRWITWLSYL
EDPRITFYYDKTLPDLKNVPETV
Ligand information
Receptor-Ligand Complex Structure
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PDB7o0h Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
Resolution3.09 Å
Binding residue
(original residue number in PDB)
R162 P537 L538
Binding residue
(residue number reindexed from 1)
R136 P482 L483
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:7o0h, PDBe:7o0h, PDBj:7o0h
PDBsum7o0h
PubMed34232702
UniProtD5JWV1

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