Structure of PDB 7ni7 Chain B Binding Site BS01

Receptor Information
>7ni7 Chain B (length=246) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDYCQHFVDTGHRPQNFIRDRELIRLKDELIAKSNTPPMYLQADIEAFDI
RELTPKFDVILLEPPLEEYYRETKCWTWDDIMKLEIDEIAAPRSFIFLWC
GSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTK
EHCLMGIKGTVVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLF
GRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7ni7 Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ni7 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D157 H332 H336
Binding residue
(residue number reindexed from 1)		D28 H185 H189
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7ni7, PDBe:7ni7, PDBj:7ni7
PDBsum7ni7
PubMed
UniProtQ9HCE5|MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Gene Name=METTL14)

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