Structure of PDB 7nfb Chain B Binding Site BS01
Receptor Information
>7nfb Chain B (length=244) Species:
9606
(Homo sapiens) [
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SLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADREL
VHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLF
APDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILL
NSGVYTFLSSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR
Ligand information
>7nfb Chain D (length=11) Species:
9606
(Homo sapiens) [
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KHKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
7nfb
A PROSS-designed extensively mutated estrogen receptor alpha variant displays enhanced thermal stability while retaining native allosteric regulation and structure.
Resolution
1.33 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 E76 D234 E238
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7nfb
,
PDBe:7nfb
,
PDBj:7nfb
PDBsum
7nfb
PubMed
34006920
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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