Structure of PDB 7n19 Chain B Binding Site BS01
Receptor Information
>7n19 Chain B (length=187) Species:
9606
(Homo sapiens) [
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RPRFLEYSTSECHFFNGTERVRYLDRYFHNQEENVRFDSDVGEFRAVTEL
GRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTVYP
SKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDW
TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
Ligand information
>7n19 Chain C (length=13) Species:
32630
(synthetic construct) [
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GGIGSDNKVTRRG
Receptor-Ligand Complex Structure
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PDB
7n19
CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope.
Resolution
2.38 Å
Binding residue
(original residue number in PDB)
E9 S11 S13 Y26 Y30 N37 D57 Y60 W61 L67 Q70 K71 R74 Y78 H81 N82 V86
Binding residue
(residue number reindexed from 1)
E6 S8 S10 Y23 Y27 N34 D54 Y57 W58 L64 Q67 K68 R71 Y75 H78 N79 V83
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:7n19
,
PDBe:7n19
,
PDBj:7n19
PDBsum
7n19
PubMed
34410304
UniProt
Q5Y7D1
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