Structure of PDB 7n02 Chain B Binding Site BS01

Receptor Information

>7n02 Chain B (length=362) Species: 1358 (Lactococcus lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAISPHERIAGLMIFRDS
TPMLFTPALEVEKAKEHTSGLDIFGYEDSQNPWEVVKNHVKSDVKSIAVE
FSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKVAGDFA
DKCFEIGFATAAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARA
ANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIGQPNDFDAEIH
KIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGM
DVHEYPSIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIEDCLYVTENGCE
SFTHTDHDLLIF

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

7n02 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7n02 Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships.
Resolution	2.35 Å
Binding residue (original residue number in PDB)	D221 D232 E339
Binding residue (residue number reindexed from 1)	D221 D232 E339
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H204 T234 E325
Catalytic site (residue number reindexed from 1)	H204 T234 E325
Enzyme Commision number	3.4.13.9: Xaa-Pro dipeptidase.

Gene Ontology

	Molecular Function
GO:0004177	aminopeptidase activity
GO:0016805	dipeptidase activity
GO:0046872	metal ion binding
GO:0102009	proline dipeptidase activity

View graph for
Molecular Function

External links

PDB	RCSB:7n02, PDBe:7n02, PDBj:7n02
PDBsum	7n02
PubMed	28179139
UniProt	A8WBX8

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