Structure of PDB 7mx1 Chain B Binding Site BS01
Receptor Information
>7mx1 Chain B (length=222) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAI
ILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYG
CCKELASRLRYARTMVDKLLSS
Ligand information
>7mx1 Chain E (length=5) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
PLAST
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7mx1
Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles.
Resolution
1.64 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 L490 L491 R516 H538 K540
Binding residue
(residue number reindexed from 1)
W43 V44 D45 L119 L120 R145 H167 K169
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:7mx1
,
PDBe:7mx1
,
PDBj:7mx1
PDBsum
7mx1
PubMed
34346472
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
[
Back to BioLiP
]
