Structure of PDB 7moi Chain B Binding Site BS01

Receptor Information
>7moi Chain B (length=154) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELHLIPPLNFSMVDNGIFRSGFPDSANFSFLQTLGLRSIIYLCPEPYPES
NLQFLKSNGIRLFQFGIEGNKEPFVNIPDHKIRMALKVLLDEKNHPVLIH
SKRGKHRTGCLVGCLRKLQKWCLTSIFDEYQRFAAAKARVSDQRFMEIFD
VSSF
Ligand information
Ligand IDHPS
InChIInChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
InChIKeyCMPQUABWPXYYSH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(Oc1ccccc1)(O)O
OpenEye OEToolkits 1.5.0c1ccc(cc1)OP(=O)(O)O
CACTVS 3.341O[P](O)(=O)Oc1ccccc1
FormulaC6 H7 O4 P
NamePHENYL DIHYDROGEN PHOSPHATE;
PHENYLPHOSPHATE
ChEMBLCHEMBL26128
DrugBankDB03298
ZINCZINC000001529512
PDB chain7moi Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7moi A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		S150 K151 R152 G153 K154 H155 R156
Binding residue
(residue number reindexed from 1)		S101 K102 R103 G104 K105 H106 R107
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7moi, PDBe:7moi, PDBj:7moi
PDBsum7moi
PubMed35468885
UniProtQ9ZVN4|DSP1_ARATH Inositol diphosphatase DSP1 (Gene Name=DSP1)

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