Structure of PDB 7lle Chain B Binding Site BS01

Receptor Information
>7lle Chain B (length=445) Species: 1877 (Micromonospora echinospora) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYRELIERARRTTAAEEYDISGRYPSVIAHAEGAWMTDLSGNRYVDLTG
ADAAVILGYRHPAVNEAITRQIRDYGTTFASTLSVPRVELAERMCERYEC
AEKVVFHKTGTEGTAMAVRLARAATGRELVLSSGYHGWHEWQMAGEEFGY
QQSTGVVGFGYNEKALAKMLEAFGEQVAGVIVSPEVLYFDLDHYRRMSAL
CARYDVPFMLDEVYTGFRAGPKGVHGLGVPADVVVLGKGLANGHSLAAVM
GRRDIIDAYDVSGIQGTYTREVPPMAAALAVFEVLDTPGVYEHAEAMGRR
LADGMREILTGEGIPNWVGGPALMFDVVLPNDDLGWEIYKTAHDFGVYFE
DSGTQLVTAAFDEAAVDHALTAFRKATRQVVADRPDIAPTSGGELTEERK
LDFAEEAFGGLLRDDERTNALIDETIEKVVNRDRSIKPVLFPAQN
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain7lle Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lle Crystal structure of GenB4 in complex with external aldimine of PLP-sisomicin
Resolution1.704 Å
Binding residue
(original residue number in PDB)		G266 T267
Binding residue
(residue number reindexed from 1)		G266 T267
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

View graph for
Molecular Function
External links
PDB RCSB:7lle, PDBe:7lle, PDBj:7lle
PDBsum7lle
PubMed
UniProtQ6QVT7

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