Structure of PDB 7l5c Chain B Binding Site BS01

Receptor Information
>7l5c Chain B (length=292) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYC
GSCAAHAYKQVDPSITRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRI
DQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIP
VLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYDES
QGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNA
ITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH
Ligand information
Ligand IDCU1
InChIInChI=1S/Cu/q+1
InChIKeyVMQMZMRVKUZKQL-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu+]
FormulaCu
NameCOPPER (I) ION
ChEMBL
DrugBank
ZINC
PDB chain7l5c Chain B Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7l5c MEMO1 is an Iron Containing Regulator of Metal Homeostasis in the Cell
Resolution2.55 Å
Binding residue
(original residue number in PDB)		H49 H81 C244
Binding residue
(residue number reindexed from 1)		H44 H76 C239
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032886 regulation of microtubule-based process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l5c, PDBe:7l5c, PDBj:7l5c
PDBsum7l5c
PubMed38640016
UniProtQ9Y316|MEMO1_HUMAN Protein MEMO1 (Gene Name=MEMO1)

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