Structure of PDB 7l49 Chain B Binding Site BS01

Receptor Information

>7l49 Chain B (length=519) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TKTLKLRIVRPYNSAEVEKIVADEKNNREKIALEKNKDKVKEACSKHLKV
AAYCTTQVERNACLFCKARKLDDKFYQKLRGQFPDAVFWQEISEIFRQLQ
KQAAEIYNQSLIELYYEIFIKGKGIANASSVEHYLSDVCYTRAAELFKNA
AIASGLRSKIKSNFRLKELKNMKSGLPTTKSDNFPIPLVKQKGGQYTGFE
ISNHNSDFIIKIPFGRWQVKKEIDKYRPWEKFDFEQVQKSPKPISLLLST
QRRKRNKGWSKDEGTEAEIKKVMNGDYQTSYIEVKRGSKICEKSAWMLNL
SIDVPKIDKGVDPSIIGGIDVGVKSPLVCAINNAFSRYSISDNDLFHFNK
KMFARRRILLKKNRHKRAGHGAKNKLKPITILTEKSERFRKKLIERWACE
IADFFIKNKVGTVQMENLESMKRKEDSYFNIRLRGFWPYAEMQNKIEFKL
KQYGIEIRKVAPNNTSKTCSKCGHLNNYFNFEYRKKNKFPHFKCEKCNFK
ENADYNAALNISNPKLKST

Ligand information

>7l49 Chain C (length=30) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccggcgacgttgggtcaacttaaatacgta

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7l49 Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	T9 K11 R258 N305 F341 S345
Binding residue (residue number reindexed from 1)	T3 K5 R252 N299 F335 S339

External links

PDB	RCSB:7l49, PDBe:7l49, PDBj:7l49
PDBsum	7l49
PubMed	33764415

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