Structure of PDB 7k7t Chain B Binding Site BS01

Receptor Information
>7k7t Chain B (length=386) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEV
KNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKPIGVFGNGFKSGSMRLGKD
ALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIIDSLPS
LEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRSELDFDTDQYDI
LVSDELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYD
TYKPTFTNKQVRITFGFSCFGIMMYHNNRLIKSFEKVGCQVGVGVIGVIE
CNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTKVPDQTWVQCDE
CLKWRKLPGIDPSMLPARWFCYYNSHPKYRCSVPEE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7k7t Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7k7t Molecular mechanism of the MORC4 ATPase activation.
Resolution2.94 Å
Binding residue
(original residue number in PDB)		C429 C432 C453 C464
Binding residue
(residue number reindexed from 1)		C348 C351 C371 C381
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7k7t, PDBe:7k7t, PDBj:7k7t
PDBsum7k7t
PubMed33122719
UniProtQ8TE76|MORC4_HUMAN MORC family CW-type zinc finger protein 4 (Gene Name=MORC4)

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