Structure of PDB 7k6q Chain B Binding Site BS01

Receptor Information
>7k6q Chain B (length=91) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKV
FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
Ligand information
>7k6q Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacggattctcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7k6q Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
T30 P32 R36 R45
Binding residue
(residue number reindexed from 1)
T20 P22 R26 R35
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7k6q, PDBe:7k6q, PDBj:7k6q
PDBsum7k6q
PubMed33479126
UniProtP62799|H4_XENLA Histone H4

[Back to BioLiP]