Structure of PDB 7k2i Chain B Binding Site BS01

Receptor Information
>7k2i Chain B (length=280) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGG
RNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVG
GSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFD
GTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQD
QLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLD
SVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7k2i Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
Resolution2.42 Å
Binding residue
(original residue number in PDB)		Y334 S363 R380 N382 R415 R483 S508 Y525 Q530 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)		Y5 S34 R51 N53 R86 R154 S179 Y196 Q201 S226 A227 Y243 F248 S273
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7k2i, PDBe:7k2i, PDBj:7k2i
PDBsum7k2i
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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