Structure of PDB 7k1a Chain B Binding Site BS01

Receptor Information

>7k1a Chain B (length=207) Species: 1196325 (Pseudomonas putida DOT-T1E) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFN
NKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVLD
ARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDIHKGWTLALANAVRRGQ
LPGELDAERAAVALYAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDMLR
LSPALRK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7k1a Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7k1a Epistasis shapes the fitness landscape of an allosteric specificity switch.
Resolution	1.75 Å
Binding residue (original residue number in PDB)	T70 E100
Binding residue (residue number reindexed from 1)	T66 E96
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0001217	DNA-binding transcription repressor activity
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0032993	protein-DNA complex

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Cellular Component

External links

PDB	RCSB:7k1a, PDBe:7k1a, PDBj:7k1a
PDBsum	7k1a
PubMed	34548494
UniProt	Q9AIU0\|TTGR_PSEPT HTH-type transcriptional regulator TtgR (Gene Name=ttgR)

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