Structure of PDB 7jof Chain B Binding Site BS01

Receptor Information
>7jof Chain B (length=126) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEG
FEWDLKGIPLDQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSA
SFNAPLLDTKKQPTGASLVLQVSYTP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7jof Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jof Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D18 I19 D21 N40
Binding residue
(residue number reindexed from 1)		D19 I20 D22 N41
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7jof, PDBe:7jof, PDBj:7jof
PDBsum7jof
PubMed33449082
UniProtO75923|DYSF_HUMAN Dysferlin (Gene Name=DYSF)

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