Structure of PDB 7go4 Chain B Binding Site BS01

Receptor Information
>7go4 Chain B (length=180) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPGFDFAQAIMKKNTVIARTEKGEFTMLGVYDRVAVIPTHASVGEIIYIN
DVETRVLDACALRDLTDTNLEITIVKLDRNQKFRDIRHFLPRCEDDYNDA
VLSVHTSKFPNMYIPVGQVTNYGFLNLGGTPTHRILMYNFPTRAGQCGGV
VTTTGKVIGIHVGGNGAQGFAAMLLHSYFT
Ligand information
Ligand IDK7L
InChIInChI=1S/C6H5N3O2/c10-4-3-5(11)9-2-1-7-6(9)8-4/h1-3,11H,(H,7,8,10)
InChIKeyBELWUABPSOOYPK-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01Oc1nc2nccn2c(O)c1
OpenEye OEToolkits 2.0.7c1cn2c(cc(nc2n1)O)O
CACTVS 3.385Oc1cc(O)n2ccnc2n1
FormulaC6 H5 N3 O2
Name(4S)-imidazo[1,2-a]pyrimidine-5,7-diol
ChEMBL
DrugBank
ZINCZINC000100006169
PDB chain7go4 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7go4 PanDDA analysis group deposition
Resolution1.49 Å
Binding residue
(original residue number in PDB)		T20 E21 I46
Binding residue
(residue number reindexed from 1)		T20 E21 I46
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7go4, PDBe:7go4, PDBj:7go4
PDBsum7go4
PubMed
UniProtQ68T42|POLG_HED68 Genome polyprotein

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