Structure of PDB 7ftb Chain B Binding Site BS01

Receptor Information
>7ftb Chain B (length=193) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFG
DQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDS
TGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIA
DILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Ligand information
Ligand IDYEZ
InChIInChI=1S/C10H6N2O2/c13-10-9-7(5-11-12-10)6-3-1-2-4-8(6)14-9/h1-5H,(H,12,13)
InChIKeyJPYPDSHHTRFKAI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7c1ccc2c(c1)c3c(o2)C(=O)NN=C3
CACTVS 3.385O=C1NN=Cc2c1oc3ccccc23
ACDLabs 12.01O=C1NN=Cc2c3ccccc3oc21
FormulaC10 H6 N2 O2
Name[1]benzofuro[2,3-d]pyridazin-4(3H)-one
ChEMBL
DrugBank
ZINCZINC000032099174
PDB chain7ftb Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ftb SDCBP PanDDA analysis group deposition
Resolution2.22 Å
Binding residue
(original residue number in PDB)		D256 I257
Binding residue
(residue number reindexed from 1)		D151 I152
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7ftb, PDBe:7ftb, PDBj:7ftb
PDBsum7ftb
PubMed
UniProtO00560|SDCB1_HUMAN Syntenin-1 (Gene Name=SDCBP)

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