Structure of PDB 7flz Chain B Binding Site BS01

Receptor Information
>7flz Chain B (length=300) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVIHFQHAD
NSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQ
MMVSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQEN
ELSDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNS
SNYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEI
LYYQIKTLPEQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELL
Ligand information
Ligand IDV6I
InChIInChI=1S/C7H8FNO2S/c1-12(10,11)9-7-5-3-2-4-6(7)8/h2-5,9H,1H3
InChIKeyDJLCKPRURZWUOU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385C[S](=O)(=O)Nc1ccccc1F
ACDLabs 12.01O=S(C)(=O)Nc1ccccc1F
OpenEye OEToolkits 2.0.7CS(=O)(=O)Nc1ccccc1F
FormulaC7 H8 F N O2 S
NameN-(2-fluorophenyl)methanesulfonamide
ChEMBL
DrugBank
ZINCZINC000000029491
PDB chain7flz Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7flz Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
Resolution1.52 Å
Binding residue
(original residue number in PDB)		T7 Y68 K88
Binding residue
(residue number reindexed from 1)		T7 Y68 K88
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7flz, PDBe:7flz, PDBj:7flz
PDBsum7flz
PubMed36260741
UniProtP32357|AAR2_YEAST A1 cistron-splicing factor AAR2 (Gene Name=AAR2)

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