Structure of PDB 7f7g Chain B Binding Site BS01
Receptor Information
>7f7g Chain B (length=183) Species:
10116
(Rattus norvegicus) [
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FVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRD
YHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILD
VSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATK
LEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLS
Ligand information
>7f7g Chain D (length=12) Species:
10116
(Rattus norvegicus) [
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RIRRDEYLKAIQ
Receptor-Ligand Complex Structure
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PDB
7f7g
Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Resolution
2.446 Å
Binding residue
(original residue number in PDB)
D545 P564 R568 R571 D579 Y580 E600 Y604 Y609 G610 T611 D629
Binding residue
(residue number reindexed from 1)
D16 P35 R39 R42 D50 Y51 E71 Y75 Y80 G81 T82 D100
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7f7g
,
PDBe:7f7g
,
PDBj:7f7g
PDBsum
7f7g
PubMed
34458841
UniProt
P31016
|DLG4_RAT Disks large homolog 4 (Gene Name=Dlg4)
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