Structure of PDB 7exj Chain B Binding Site BS01

Receptor Information
>7exj Chain B (length=718) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PAVRISDGNLIIKNRTILTGVPDNVITTSASEAGPVEGVFVGAVFNKEES
KHIVPIGTLRNSRFMSCFRFKLWWMAQRMGEMGRDIPYETQFLLVESNKV
YTVFLPLIEGSFRSCLQGNVNDEVELCLESGDVDTKRSSFTHSLYIHAGT
DPFQTITDAIRTVKLHLNSFRQRHEKKLPGIVDYFGWCTWDAFYQEVTQE
GVEAGLKSLAAGGTPPKFVIIDDGWQSVERDASPIFRLTGIKENEKFKKK
DDPNVGIKNIVKIAKEKHGLRYVYVWHAITGYWGGVRPGEEYGSVMKYPN
MSKGVVENDPTWKTDVMTLQGLGLVSPKKVYKFYNELHSYLADAGVDGVK
VAVQCVLETLGGGLGGRVELTRQFHQALDSSVAKNFPDNGCIACMSHNTD
ALYCSKQAAVIRASDDFYPRDPVSHTIHIASVAYNSVFLGEFMQPDWDMF
HSVHPAAEYHASARAISGGPLYVSDSPGKHNFELLRKLVLPDGSILRARL
PGRPTRDCLFADPARDGVSLLKIWNMNKYTGVLGVYNCQGAAWSSTERKN
IFHQTKTDSLTGSIRGRDVHSISEASTDPTTWNGDCAVYSQSRGELIVMP
YNVSLPVSLKIREHEIFTVSPISHLVDGVSFAPIGLVNMYNSGGAIEGLR
YEAEKMKVVMEVKGCGKFGSYSSVKPKRCVVESNEIAFEYDSSSGLVTFE
LDKMPIENKRFHLIQVEL
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain7exj Chain D Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7exj Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		K75 W78 M426 D446 D447
Binding residue
(residue number reindexed from 1)		K71 W74 M395 D415 D416
Annotation score2
Enzymatic activity
Enzyme Commision number 2.4.1.82: galactinol--sucrose galactosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0047274 galactinol-sucrose galactosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7exj, PDBe:7exj, PDBj:7exj
PDBsum7exj
PubMed36762861
UniProtQ8RX87|RFS6_ARATH Probable galactinol--sucrose galactosyltransferase 6 (Gene Name=RFS6)

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