Structure of PDB 7ej3 Chain B Binding Site BS01

Receptor Information

>7ej3 Chain B (length=401) Species: 44752 (Rhodococcus wratislaviensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HSGGVGALPIHWGAPTASERGPVVGTTTNRAHRNVIGTHSGSYSIYRALA
VASGALSRHHKADLTDTAPTNIIGPYPQWSQPGKIVSLDPWGATVAEVFA
AELAAGHDIRPSIAVTKAHVILPEVMEAIQKGRLHPDGRFLLPSGAALVT
KAAIEPVWHLPGVAERFHCSETDLRRVLFEETGGMYPELVTRSDLEVFLP
PIGGQTVYIFGDARDLADPGVELTARVHDECNGSDVFGSDICTCRPYLTH
AIEECIQGAQRGGVGLVAYSRKEGRALGEVTKFLVYNARKRQVGGDTADQ
YFARTECVAGVQDMRFQEMMPDVLHWLGVRKIHRLVSMSNMKYDAITGSG
IEVVERVDLPADLIPADARVEIDAKMAAGYFTPGAVPDADELAKVKGREL
D

Ligand information

Ligand ID

GLY

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.5.0	C(C(=O)O)N
CACTVS 3.341	NCC(O)=O
ACDLabs 10.04	O=C(O)CN

Formula

C2 H5 N O2

Name

GLYCINE

PDB chain

7ej3 Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7ej3 Structural and biochemical investigation of UTP cyclohydrolase
Resolution	1.6 Å
Binding residue (original residue number in PDB)	E422 L423 D424
Binding residue (residue number reindexed from 1)	E399 L400 D401
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003935	GTP cyclohydrolase II activity
GO:0005525	GTP binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009231	riboflavin biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:7ej3, PDBe:7ej3, PDBj:7ej3
PDBsum	7ej3
PubMed
UniProt	A0A3D9R4E8

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