Structure of PDB 7ebr Chain B Binding Site BS01

Receptor Information
>7ebr Chain B (length=228) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVPTYLLPGSGQFLTTDDHSSAPALPCFNPTPEMHIPGQVRNMLEVVQVE
SMMEINNTESAVGMERLKVDISALTDVDQLLFNIPLDIQLDGPLRNTLVG
NISRYYTHWSGSLEMTFMFCGSFMAAGKLILCYTPPGGSCPTTRETAMLG
THIVWDFGLQSSVTLIIPWISGSHYRMFNNANVGYVTCFMQTNLIVPSES
SDTCSLIGFIAAKDDFSLRLMRDSPDIG
Ligand information
>7ebr Chain D (length=28) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
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PDB7ebr Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D18 S20 S21 A22 P23 L25 R41 N42 E45 Q48
Binding residue
(residue number reindexed from 1)		D18 S20 S21 A22 P23 L25 R41 N42 E45 Q48
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:7ebr, PDBe:7ebr, PDBj:7ebr
PDBsum7ebr
PubMed34006855
UniProtA0A097BW12

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