Structure of PDB 7ea4 Chain B Binding Site BS01

Receptor Information
>7ea4 Chain B (length=761) Species: 1744839 (Cupriavidus sp. P4-10-C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQID
LWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAE
AFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGETLN
FTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAAL
KKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLR
YVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYET
DPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADD
ASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQV
YADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYN
PSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSL
RDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGW
DGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAV
LEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFR
HPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMV
LDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVER
AAEKRIELTPR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7ea4 Chain B Residue 904 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7ea4 Protein Engineering of d-Succinylase from Cupriavidus sp. for d-Amino Acid Synthesis and the Structural Implications.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		N185 E189 D354 E356 D357 G487
Binding residue
(residue number reindexed from 1)		N150 E154 D291 E293 D294 G424
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7ea4, PDBe:7ea4, PDBj:7ea4
PDBsum7ea4
PubMed
UniProtA0A0N7KZ58

[Back to BioLiP]