Structure of PDB 7dxi Chain B Binding Site BS01

Receptor Information
>7dxi Chain B (length=371) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACTAIDAVYTWVNGSDPNFIEDIRRFKNELRYSLRSLEKHAAWIRHVYIV
TNGQIPSWLDLSYERVTVVPHEVLAPDPDQLPTFSSSAIETFLHRIPKLS
KRFLYLNDDIFLGAPLYPEDLYTEAEGVRVYQATDIYSHSLIATNMLLNR
AYGFKARHVLAHVGFLIDKDIVEAMQRRFHQQILDTAHQRFRAPTDLQYA
FAYYSFLMSETKVMSVEEIFDEFDTDGSATWSDREVRTFLTRIYQPPLDW
SAMRYFEEVVQNCTLPTITRDLVVRCPLLAEALAANFAVRPKYNFHVSPK
RTSHSNFMMLTSNLTEVVESLDRLRRNPRKFNCINDNLDANRGEDNEMVR
HLLEDFYLSFFPRRSKFELPP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7dxi Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7dxi Structural insights into how GlcNAc-1-phosphotransferase directs lysosomal protein transport.
Resolution3.53 Å
Binding residue
(original residue number in PDB)		D437 D439 T443 E448
Binding residue
(residue number reindexed from 1)		D224 D226 T230 E235
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:7dxi, PDBe:7dxi, PDBj:7dxi
PDBsum7dxi
PubMed35148990
UniProtA1Z7S7

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