Structure of PDB 7ds2 Chain B Binding Site BS01

Receptor Information
>7ds2 Chain B (length=235) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARD
KVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANN
AFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGKKIKGCWDSIHVVE
VQEKTAHYKLTSTVMLWLQTNKTGSGTMNLGGSLTRQMEKDETVSDSSPH
IANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLR
Ligand information
>7ds2 Chain C (length=23) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AHKQSFAKPKGPAGKRGIRRLIR
Receptor-Ligand Complex Structure
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PDB7ds2 Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		E22 S26 E37 L40 S41 D63 Y64 R66 D67 G68 Y71 W122 L124 V153 E155 K168 R195 Q196 M197
Binding residue
(residue number reindexed from 1)		E20 S24 E35 L38 S39 D61 Y62 R64 D65 G66 Y69 W120 L122 V148 E150 K159 R186 Q187 M188
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0051016 barbed-end actin filament capping
Cellular Component
GO:0005737 cytoplasm
GO:0008290 F-actin capping protein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ds2, PDBe:7ds2, PDBj:7ds2
PDBsum7ds2
PubMed33639213
UniProtP14315|CAPZB_CHICK F-actin-capping protein subunit beta isoforms 1 and 2 (Gene Name=CAPZB)

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