Structure of PDB 7dh6 Chain B Binding Site BS01

Receptor Information
>7dh6 Chain B (length=294) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK
LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLS
AVYGLDLHPTIDVLVTCSRDSTARIWDVRSVHTLSGHTNAVATVRCQAAE
PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSP
DNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWDWR
TGYNFQRVHAALDSESGIFACAFDQSESRLLTAEADKTIKVYRE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7dh6 Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7dh6 Crystal structure of the WD40 domain of human PLRG1.
Resolution2.584 Å
Binding residue
(original residue number in PDB)		D432 D460 S463
Binding residue
(residue number reindexed from 1)		D240 D263 S266
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome

View graph for
Biological Process
External links
PDB RCSB:7dh6, PDBe:7dh6, PDBj:7dh6
PDBsum7dh6
PubMed33239170
UniProtO43660|PLRG1_HUMAN Pleiotropic regulator 1 (Gene Name=PLRG1)

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