Structure of PDB 7d6x Chain B Binding Site BS01

Receptor Information
>7d6x Chain B (length=239) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATYDAKLRVWRGDDTGGELHDYTVEVNDGEVVLDIIHRLQATQTPDLAVR
WNCKAGKCGSCSAEINGRPRLMCMTRMSTFGEDEVVTVTPLRTFPVMRDL
VTDVSFNYEKARQIPSFTPPKDLQPGEYRMQQEDVNRSQEFRKCIECFLC
QNVCHVVRDHEENKENFAGPRFHMRIAELDMHPLDTVDRKEMAQDEFGLG
YCNITKCCTEVCPEHIKITDNALIPMKERVADRKYDPIV
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7d6x Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7d6x Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.
Resolution2.88 Å
Binding residue
(original residue number in PDB)		C54 K55 C59 C62 C74
Binding residue
(residue number reindexed from 1)		C53 K54 C58 C61 C73
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d6x, PDBe:7d6x, PDBj:7d6x
PDBsum7d6x
PubMed33876763
UniProtA0QPJ2

[Back to BioLiP]