Structure of PDB 7d6v Chain B Binding Site BS01

Receptor Information

>7d6v Chain B (length=239) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATYDAKLRVWRGDDTGGELHDYTVEVNDGEVVLDIIHRLQATQTPDLAVR
WNCKAGKCGSCSAEINGRPRLMCMTRMSTFGEDEVVTVTPLRTFPVMRDL
VTDVSFNYEKARQIPSFTPPKDLQPGEYRMQQEDVNRSQEFRKCIECFLC
QNVCHVVRDHEENKENFAGPRFHMRIAELDMHPLDTVDRKEMAQDEFGLG
YCNITKCCTEVCPEHIKITDNALIPMKERVADRKYDPIV

Ligand information

InChI=1S/2Fe.2S

NIXDOXVAJZFRNF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04	[Fe]1S[Fe]S1
CACTVS 3.341 OpenEye OEToolkits 1.5.0	S1[Fe]S[Fe]1

Formula

Fe2 S2

Name

FE2/S2 (INORGANIC) CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

7d6v Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7d6v Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.
Resolution	2.53 Å
Binding residue (original residue number in PDB)	C54 K55 G57 C59 G60 C62 C74
Binding residue (residue number reindexed from 1)	C53 K54 G56 C58 G59 C61 C73
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0009055	electron transfer activity
GO:0016491	oxidoreductase activity
GO:0051536	iron-sulfur cluster binding
GO:0051537	2 iron, 2 sulfur cluster binding

	Biological Process
GO:0006099	tricarboxylic acid cycle
GO:0009060	aerobic respiration
GO:0022904	respiratory electron transport chain

	Cellular Component
GO:0005886	plasma membrane

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External links

PDB	RCSB:7d6v, PDBe:7d6v, PDBj:7d6v
PDBsum	7d6v
PubMed	33876763
UniProt	A0QPJ2

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