Structure of PDB 7cyy Chain B Binding Site BS01

Receptor Information
>7cyy Chain B (length=494) Species: 1388,235909,1202714 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRFPFPFVFKS
VVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLH
LHTQFNRDIPWDSIDMDFMNLNQSAHGDREFGFMVTRLGMPRKVIVGHWQ
DAEVARRVRGWAMTAVAAAVSRGLKVARFGDNMRQVAVTEGDKVEAEARF
GWSVNGYGVGDLAERVRAVSEAEIDRLIDEYQSLYEFAPGCEKGGPLHDG
VREQARIELGLRSFLEEGGFEAFTTTFEDLHGMKQLPGLAVQRLMAEGYG
FGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNEMILGAHMLEV
CPTIAATRPRIEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRL
IVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSF
AVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRGR
Ligand information
Ligand IDRB0
InChIInChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5-
InChIKeyHEBKCHPVOIAQTA-ZXFHETKHSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C(C(C(CO)O)O)O)O
CACTVS 3.370OC[CH](O)[CH](O)[CH](O)CO
ACDLabs 12.01OC(CO)C(O)C(O)CO
OpenEye OEToolkits 1.7.6C([C@H](C([C@H](CO)O)O)O)O
CACTVS 3.370OC[C@H](O)[C@H](O)[C@H](O)CO
FormulaC5 H12 O5
NameD-ribitol
ChEMBLCHEMBL3137744
DrugBankDB14704
ZINCZINC000100014205
PDB chain7cyy Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cyy Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI8 with Adonitol
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E307 E332 H447 H448
Binding residue
(residue number reindexed from 1)		E304 E329 H444 H445
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005996 monosaccharide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cyy, PDBe:7cyy, PDBj:7cyy
PDBsum7cyy
PubMed
UniProtK0IGW6;
Q2VMT2;
Q5KYP7|ARAA_GEOKA L-arabinose isomerase (Gene Name=araA)

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