Structure of PDB 7cxo Chain B Binding Site BS01

Receptor Information
>7cxo Chain B (length=496) Species: 83333,235909,1202714 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKMPAYEFWFVVGSQHLYGDEALAQVEAHAREMVPALQAAVGNAHVLRWK
GVLKDADEIRRLCLEASADDVCAGVIAWMHTFSPAKMWIRGLLALRKPLL
HLHTQFNRDIPWDTIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHW
EDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQ
FGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRE
SIREQARIELGLKAFLQDGNFTAFTTTFEDLHGLKQLPGLAVQRLMQQGY
GFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHM
LEVCPSIAAEEKPILDVQHLGIGGKDDPARLVFDGGEGAAVNASLIDLGH
RFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHT
CFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cxo Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cxo Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI10
Resolution3.2 Å
Binding residue
(original residue number in PDB)		E305 E332 H349 H449
Binding residue
(residue number reindexed from 1)		E305 E332 H349 H449
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005996 monosaccharide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cxo, PDBe:7cxo, PDBj:7cxo
PDBsum7cxo
PubMed
UniProtK0IGW6;
P08202|ARAA_ECOLI L-arabinose isomerase (Gene Name=araA);
Q5KYP7|ARAA_GEOKA L-arabinose isomerase (Gene Name=araA)

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