Structure of PDB 7cec Chain B Binding Site BS01

Receptor Information
>7cec Chain B (length=427) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRCLKANAKSCGECIQAGPNCGWCTNSTFLTSARCDDLEALKKKGCPPDD
IENPRGSKDIKKNKNVTNLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKR
AEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSF
VEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVG
KQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGD
GKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAV
TEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENG
KLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPK
KDSDSFKIRPLGFTEEVEVILQYICEC
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cec Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cec Structural mechanism of laminin recognition by integrin.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		E169 N224 D226 P228 E229
Binding residue
(residue number reindexed from 1)		E152 N207 D209 P211 E212
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7cec, PDBe:7cec, PDBj:7cec
PDBsum7cec
PubMed34188035
UniProtP05556|ITB1_HUMAN Integrin beta-1 (Gene Name=ITGB1)

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