Structure of PDB 7c5v Chain B Binding Site BS01

Receptor Information
>7c5v Chain B (length=163) Species: 103690 (Nostoc sp. PCC 7120 = FACHB-418) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTPIVNRAITESEVLAAQKAWGEALVAISTTYDAKGKASAKALAEKVIDD
AYGYQFGPVLFKPTLAISPRTFRTTRAGALAYFVGDDKAFPEDKGFALSS
WRKVEIKNAAIFITGNTATTMGNVIITDKQGKATTVDKTWQFLKDDHGKL
RIITHHSSLPYEQ
Ligand information
Ligand IDBCT
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)(O)[O-]
CACTVS 3.341OC([O-])=O
ACDLabs 10.04[O-]C(=O)O
FormulaC H O3
NameBICARBONATE ION
ChEMBL
DrugBank
ZINC
PDB chain7c5v Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c5v Characterization of a novel type of carbonic anhydrase that acts without metal cofactors.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		P105 T106 Y124 F138
Binding residue
(residue number reindexed from 1)		P63 T64 Y82 F96
Annotation score5
Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7c5v, PDBe:7c5v, PDBj:7c5v
PDBsum7c5v
PubMed34006275
UniProtQ8YT18|MICAH_NOSS1 Metal-independent carbonic anhydrase (Gene Name=all2909)

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