Structure of PDB 7c29 Chain B Binding Site BS01

Receptor Information
>7c29 Chain B (length=188) Species: 450378 (Croceicoccus marinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPAIDVLAFGDSLFAGYRLDRDESYPARLQAALRERGLNVNVTNAGVSGD
TTAAGLQRIDFVLDSMAGEPDLVLLELGANDMLRGLPAEEARRNLDTILQ
RLDQRDIPVMVYGMRAAPNLGGDYGRSFDSIFPDLADKYDAELVPFFIEP
LIFDRSLVQQAQLHPTAQGVDAMVEQTVEQVEDRIDDL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7c29 Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c29 Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases.
Resolution2.18 Å
Binding residue
(original residue number in PDB)		E86 D123
Binding residue
(residue number reindexed from 1)		E69 D106
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004622 lysophospholipase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7c29, PDBe:7c29, PDBj:7c29
PDBsum7c29
PubMed32549911
UniProtA0A1Z1F9L9

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