Structure of PDB 7c1z Chain B Binding Site BS01

Receptor Information

>7c1z Chain B (length=355) Species: 3702 (Arabidopsis thaliana)

MEPVIIGALILDVHAKPSTTPISGTTVPGQVLFAPGGVARNVADCIFKLG
ITPFMIGTLGLDGPANVLLKEWKLSMKGILRREDISTPIVSLVYDTNGEV
AAGVAGVDAVENFLTPEWIQRFEYNISSARLLMVDANLSSLALEASCKLA
AESSVPVWFEPVSVTKSQRIASIAKYVTIVSPNQDELIAMANALCAKNLF
HPFENKLSIEDMFRALKPAILVLLKNGVKVVIVTLGSNGALLCSKGNPKK
ALNIDSGEVFKRVQSVCSPNRFSLFAMHFPTIPAKVKKLTGAGDCLVGGT
VASLSDGLDLIQSLAVGIASAKAAVESDDNVPPEFKLDLISGDAELVYNG
AKMLM

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7c1z Chain B Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7c1z Structural basis for the substrate specificity and catalytic features of pseudouridine kinase from Arabidopsis thaliana.
• Resolution: 2.09617 Å
• Binding residue (original residue number in PDB): S181 T237
• Binding residue (residue number reindexed from 1): S181 T234
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.83: pseudouridine kinase.

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016301 kinase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0016310 phosphorylation

Cellular Component

• GO:0005777 peroxisome

External links

• PDB: RCSB:7c1z, PDBe:7c1z, PDBj:7c1z
• PDBsum: 7c1z
• PubMed: 33290549
• UniProt: Q94AT3|PUKI_ARATH Pseudouridine kinase (Gene Name=PUKI)